N6-Benzoyl-3’-O-(4,4’-dimethyltrityl)-2’-deoxyadenosine 5’-O-CED phosphoramidite

驻马店N6-Benzoyl-3’-O-(4,4’-dimethyltrityl)-2’-deoxyadenosine 5’-O-CED phosphoramidite

Used for the synthesis of reverse oligonucleotides

N6-Benzoyl-5’-O-(4,4’-dimethyltrityl)-2’-deoxyadenosine

驻马店N6-Benzoyl-5’-O-(4,4’-dimethyltrityl)-2’-deoxyadenosine

Used to make 5’-O-CED-phosphoramidite and further for the synthesis of reverse oligonucleotides

2-Thiocytidine

驻马店2-Thiocytidine

Naturally-occurring RNA modified nucleoside s2C for vaccine and cancer research. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. It binds to the catalytic site of ribonucleotide reductase and inhibits the enzyme activity, therefore, inhibiting DNA synthesis. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. 2-Thiocytidine is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B.

3’-Deoxycytidine

驻马店3’-Deoxycytidine

It is an inhibitor of RNA synthesis, but does not affect the appearance of the mRNA. It also shows inhibitory properties against hepatitis C virus-like RNA template replication.

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