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2’-Deoxy-2’-fluoro-beta-D-arabinocytidine hydrochloride

Catalog No:

Classification：

Drug Substances

Application & Biological Property：

Application & Biological Property Anticancer agent; Metabolite of Fiacitabine (FIAC); Related substance of Azvudine抗肿瘤药、非西他滨代谢物、阿兹夫定有关物质
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Product Details

Catalog No. P1028 
Name 2’-Deoxy-2’-fluoro-beta-D-arabinocytidine hydrochloride
Synonyms  
中文名称 2’-脱氧-2’-氟-阿糖胞苷
Formula C9H12FN3O4
FW 245.21
CAS No. 56632-83-8
HPLC ≥ 97%
Package Packed as desired
Classification Drug Substances; Nucleoside Derivatives; Metabolites and Related Substances  
Property Appearance and Property: white foam powder
m. p.: 136-138 °C (lit.)
Acidity (pKa): 12.84 (Predicted)
Storage: sealed vial under inert atmosphere at 2-8 °C or room temperature
Application & Biological Property Anticancer agent; Metabolite of Fiacitabine (FIAC); Related substance of Azvudine抗肿瘤药、非西他滨代谢物、阿兹夫定有关物质
References
  1. Philips, F. S., Feinberg, A., Chou, T. C., Vidal, P. M., Su, T. L., Watanabe, K. A., Fox, J. J. Cancer Res. 1983, 43, 3619-3627.
  2. Chou, T. C., Feinberg, A., Grant, A. J., Vidal, P., Reichman, U., Watanabe, K. A., Fox, J. J., Philips, F. S. Cancer Res. 1981, 41, 3336-3342.
  3. Schinazi, R. F., Fox, J. J., Watanabe, K. A., Nahmias, A. J. Antimicrob. Agents & Chemother. 1986, 29, 77-84.
  4. Kong, X. B., Andreeff, M., Fanucchi, M. P., Fox, J. J., Watanabe, K. A., Vidal, P., Chou, T. C. Leukemia Res. 1987, 11, 1031-1039.
  5. Kong, X. B., Scheck, A. C., Price, R. W., Vidal, P. M., Fanucchi, M. P., Watanabe, K. A., Fox, J. J., Chou, T. C. Antiviral Res. 1988, 10, 153-166.
  6. Watanabe, K. A., Reichman, Z. U., Hirota, K., Lopez, C., Fox, J., J. Med. Chem. 1979, 22, 21-24.

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