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2-Thiocytidine

Catalog No:

Classification：

Nucleoside Derivatives

Application & Biological Property：

Naturally-occurring RNA modified nucleoside s2C for vaccine and cancer research. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. It binds to the catalytic site of ribonucleotide reductase and inhibits the enzyme activity, therefore, inhibiting DNA synthesis. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. 2-Thiocytidine is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B.
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Product Details

Catalog No.

P1135

Name

2-Thiocytidine

Synonyms

 

中文名称

2-硫代胞苷

Formula

C9H13N3O4S

FW

259.28

CAS No.

13239-97-9

Purity

≥ 98%

Property

Appearance and Property: yellow solid, hygroscopic

m. p.: 208–209 °C

Solubility: slightly soluble in methanol and water

Storage: sealed at 2–8 °C or room temperature

Package

Packed as desired

Classification

Nucleoside Derivatives

Application & Biological Property

Naturally-occurring RNA modified nucleoside s2C for vaccine and cancer research. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. It binds to the catalytic site of ribonucleotide reductase and inhibits the enzyme activity, therefore, inhibiting DNA synthesis. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. 2-Thiocytidine is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B.

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