2’-O-Methyladenosine
Catalog No:
Classification:
Nucleoside Derivatives
Application & Biological Property:
Product Details
|
Catalog No. |
P1148 |
|
Name |
2’-O-Methyladenosine |
|
Synonyms |
|
|
中文名称 |
2’-O-甲基腺苷 |
|
Formula |
C11H15N5O4 |
|
FW |
281.27 |
|
CAS No. |
2140-79-6 |
|
Purity |
≥ 98% |
|
Property |
Appearance and Property: white solid m. p.: 200–202 ℃ Solubility: slightly soluble in DMSO, methanol (heat) and water Storage: sealed at 2–8 °C or at room temperature |
|
Package |
Packed as desired |
|
Classification |
Nucleoside Derivatives |
|
Application & Biological Property |
Naturally-occurring RNA modified nucleoside Am for vaccine and cancer research; efficiently used in antisense and siRNA medicines by increasing stability of drugs. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. It has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). It inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. |
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