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2’-O-Methyladenosine

Catalog No:

Classification:

Nucleoside Derivatives

Application & Biological Property:

Naturally-occurring RNA modified nucleoside Am for vaccine and cancer research; efficiently used in antisense and siRNA medicines by increasing stability of drugs. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. It has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). It inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides.
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Product Details


Catalog No.

P1148

Name

2-O-Methyladenosine

Synonyms

 

中文名称

2-O-甲基腺苷

Formula

C11H15N5O4

FW

281.27

CAS No.

2140-79-6

Purity

≥ 98%

Property

Appearance and Property: white solid

m. p.: 200202 ℃

Solubility: slightly soluble in DMSO, methanol (heat) and water

Storage: sealed at 28 °C or at room temperature

Package

Packed as desired

Classification

Nucleoside Derivatives

Application & Biological Property

Naturally-occurring RNA modified nucleoside Am for vaccine and cancer research; efficiently used in antisense and siRNA medicines by increasing stability of drugs. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. It has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). It inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides.

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