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5,6-Dihydro-2’-deoxyuridine

Catalog No:

P1176

Classification：

Nucleoside Derivatives

Application & Biological Property：

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Product Details

Catalog No.

P1176

Name

5,6-Dihydro-2’-deoxyuridine

Synonyms

 

中文名称

5,6-二氢-2’-脱氧尿苷

Formula

C9H14N2O5

FW

230.22

CAS No.

5626-99-3

Purity

≥ 98%

Property

Appearance and Property: white or off-white solid  

Solubility: soluble in DMSO, slightly soluble in methanol and water

Storage: sealed container at 2–8 °C or at room temperature

Package

Packed as desired

Classification

Nucleoside Derivatives

Application & Biological Property

Modified DNA building block; 5,6-Dihydro-2’-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of modified DNAs. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. It was found to inhibit viral growth and terminate replication. It also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1.

References

 

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