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5-Hydroxymethyl-2’-deoxyuridine

Catalog No:

Classification:

Biologically Important Derivatives

Application & Biological Property:

Antiviral and anticancer agent; oxidative DNA damage product, marker of breast cancer
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Product Details


Catalog No. P1013
Name 5-Hydroxymethyl-2’-deoxyuridine
Synonyms  
Formula C10H14N2O6
FW 258.23
CAS No. 5116-24-5
HPLC ≥ 97%
Package Packed as desired
Classification Drug substance; Derivatives with important biological activities
Property Appearance and Property: white to off-white solid; hygroscopic
m. p.: 176-179 °C (lit.)
Density: 1.3598 g/cm3 (estimated)
Solubility: slightly soluble in DMSO, ethanol and water
Storage: sealed at 2-8 °C or room temperature
Acidity (pKa): 9.01 (Predicted)
Application & Biological Property Antiviral and anticancer agent; oxidative DNA damage product, marker of breast cancer
References
  1. Boorstein, R. J., Teebor, G. W. Cancer Res. 1989, 49, 1509-1514.
  2. Birnbaum, G. I., Deslauriers, R., Lin, T. S., Shiau, G. T., Prusoff, W. H. J. Am. Chem. Soc. 1980, 102, 4236-4241.  
  3. Vilpo, J. A., Bergstrom, D., Kangas, L., Suvanto, E. Nucleosides, Nucleotides and Nucleic Acids 1987, 6, 415-417.

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