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5-Iodo-2’-deoxy-2’-fluoro-beta-D-arabinouridine, Fialuridine

Catalog No:

Classification：

Drug Substances

Application & Biological Property：

Antiviral drug, HBV drug
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Product Details

Catalog No. P1015
Name 5-Iodo-2’-deoxy-2’-fluoro-beta-D-arabinouridine, Fialuridine
Synonyms FIRU
Formula C9H10FIN2O5
FW 372.089
CAS No. 69123-98-4
HPLC ≥ 97%
Package Packaged as requested
Classification Drug substance; Nucleoside derivative
Property Appearance and Property: white to off-white solid or powder
m. p.: 216-217 °C (lit.)
Density: 2.180 g/cm3 (estimated)
Solubility: slightly soluble in DMSO
Storage: sealed at 2-8 °C or room temperature
Acidity (pKa): 7.94 (Predicted)
Application & Biological Property Antiviral drug, HBV drug
References
  1. Philips, F. S., Feinberg, A., Chou, T. C., Vidal, P. M., Su, T. L., Watanabe, K. A., Fox, J. J. Cancer Res. 1983, 43, 3619-3627.
  2. Chou, T. C., Feinberg, A., Grant, A. J., Vidal, P., Reichman, U., Watanabe, K. A., Fox, J. J., Philips, F. S. Cancer Res. 1981, 41, 3336-3342.
  3. Schinazi, R. F., Fox, J. J., Watanabe, K. A., Nahmias, A. J. Antimicrob. Agents & Chemother. 1986, 29, 77-84.
  4. Kong, X. B., Andreeff, M., Fanucchi, M. P., Fox, J. J., Watanabe, K. A., Vidal, P., Chou, T. C. Leukemia Res. 1987, 11, 1031-1039.
  5. Kong, X. B., Scheck, A. C., Price, R. W., Vidal, P. M., Fanucchi, M. P., Watanabe, K. A., Fox, J. J., Chou, T. C. Antiviral Res. 1988, 10, 153-166.
  6. Watanabe, K. A., Reichman, Z. U., Hirota, K., Lopez, C., Fox, J., J. Med. Chem. 1979, 22, 21-24.

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