3’-Deoxyuridine

驻马店3’-Deoxyuridine

RNA chain terminator; 3’-Deoxyuridine is a synthetic antibiotic that is used in the treatment of viral infections, such as hepatitis B and C, HIV and human cytomegalovirus (CMV). It competitively inhibits the synthesis of RNA by binding to the enzyme RNA polymerase.

Arabino inosine

驻马店Arabino inosine

Antimetabolic nucleoside; antiviral agent; Nelarabine Impurity 2, 奈拉滨杂质2; It has been shown to inhibit Streptococcus pyogenes and other bacteria. It has also been shown to have inhibitory properties against zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant.

5-Methoxycarbonylmethyl-2-thiouridine

驻马店5-Methoxycarbonylmethyl-2-thiouridine

Naturally-occurring RNA-modified nucleoside mcm5s2U, isolated from yeast tRNA, for vaccine and cancer research. It is a nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria. It can be used in biological study for attomole quantification and global profile of RNA modifications in study of human neural stem cells.

2’-O-Methyl-N1-methyl adenosine

驻马店2’-O-Methyl-N1-methyl adenosine

Naturally-occurring RNA modified nucleoside m1Am found in tRNA for vaccine and cancer research. It is a structural isomer of N6-methyl adenosine (m6A), which is the most abundant internally modified base in messenger RNA (mRNA) and non-coding RNA (ncRNA) in eukaryotic cells. It was also found from different organisms, including yeast, plants, and human cells. Its monophosphate is an antiviral agent. It has been shown to be a potent activator of the tRNA synthetase enzyme and also inhibits viral DNA synthesis. It has been shown to be highly active against viruses such as HIV-1, HIV-2, and HCV. It is also used in the production of modified nucleosides for use in synthetic constructs with therapeutic applications. It has been shown to play a role in regulating gene expression and RNA stability.

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